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US Patent 6987175 Processes for preparing clarithromycin polymorphs

Patent 6987175 was granted and assigned to Teva Pharmaceutical Industries on January, 2006 by the United States Patent and Trademark Office.

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Patent
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Patent attributes

Current Assignee
Teva Pharmaceutical Industries
Teva Pharmaceutical Industries
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Patent Jurisdiction
United States Patent and Trademark Office
United States Patent and Trademark Office
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Patent Number
69871750
Patent Inventor Names
Igor Lifshitz0
Basem Masarwa0
Edi Schwartz0
Ilya Avrutov0
Date of Patent
January 17, 2006
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Patent Application Number
104591780
Date Filed
June 10, 2003
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Patent Primary Examiner
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Elli Peselev
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Patent abstract

The present invention relates to processes for converting clarithromycin Form I to clarithromycin Form II, which include slurrying clarithromycin the Form I in water. The present invention also relates to processes for the preparation of clarithromycin Form II by converting erythromycin A to clarithromycin and thereafter converting clarithromycin Form I to clarithromycin Form II by slurrying.

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