Is a
Patent attributes
Current Assignee
Patent Jurisdiction
Patent Number
Patent Inventor Names
Valeri Martichonok0
Danny P. C. McGee0
David J. King0
Guoxian Wu0
Howard P. Ng0
Oliver L. Saunders0
Sharon Boyd0
Thomas J. Lobl0
...
Date of Patent
January 24, 2006
0Patent Application Number
101612330
Date Filed
May 31, 2002
0Patent Citations Received
0
...
Patent Primary Examiner
Patent abstract
The present invention provides analogues of duocarmycins that are potent cytotoxins. Also provided are peptidyl and disulfide linkers that are cleaved in vivo. The linkers are of use in forming prodrugs and conjugates of the cytotoxins of the invention as well as other diagnostic and therapeutic moieties. The invention provides prodrugs and conjugates of the duocarmycin analogues with the linker arms of the invention.
Timeline
No Timeline data yet.
Further Resources
No Further Resources data yet.
