US Patent 7011846 Oral capsule formulation with increased physical stability
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Patent abstract
A formulation for a stabilized capsule for oral administration of a hydrophobic pharmaceutically active agent; comprising a non-aqueous solubilizer selected from 2-pyrrolidone, N-alkylpyrrolidones and combinations thereof; and a capsule stabilizing agent selected from mono-, di- and triglycerides, mono- and di-fatty esters of polyethylene glycol, fatty acids and combinations thereof wherein capsule integrity is maintained for at least 24 hours is disclosed.
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Patent Inventor Names
Amir H. Shojaei0
Beth A. Burnside0
Scott A. Ibrahim0
Date of Patent
March 14, 2006
0Patent Application Number
103249540
Date Filed
December 20, 2002
0Patent Primary Examiner
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US Patent 7011846 Oral capsule formulation with increased physical stability
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