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US Patent 7033607 pH-titratable polyampholytes for delivering polyions to a cell

Patent 7033607 was granted and assigned to Mirus Bio on April, 2006 by the United States Patent and Trademark Office.

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Patent abstract

A polyampholyte is utilized in a condensed polynucleotide complex for purposes of nucleic acid delivery to a cell. The complex can be formed with an appropriate amount of positive and/or negative charge such that the resulting complex can be delivered to the extravascular space and may be further delivered to a cell.

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