Is a
Patent attributes
Patent Jurisdiction
Patent Number
Patent Inventor Names
Mary Collins0
Beatriz M. Carreno0
Clive Wood0
Denise O'Hara0
Donna Morris0
Gary S. Gray0
Katherine Turner0
Naoya Tsurushita0
...
Date of Patent
April 25, 2006
0Patent Application Number
097721030
Date Filed
January 26, 2001
0Patent Citations Received
Patent Primary Examiner
Patent abstract
The invention provides an antibody-toxic moiety conjugates comprising an antibody that specifically recognizes a molecule expressed on the surface of a T cell which is expressed only on T cells and is only expressed transiently on T cells upon T cell activation. Preferably, the T cell molecule is CTLA4. The invention further provides anti-CTLA4 antibodies and humanized forms thereof.
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