Is a
Patent attributes
Patent Jurisdiction
Patent Number
Patent Inventor Names
Dong-Myung Kim0
James Robert Swartz0
Date of Patent
May 9, 2006
0Patent Application Number
104045990
Date Filed
March 31, 2003
0Patent Citations Received
Patent Primary Examiner
Patent abstract
Compositions and methods are provided for the enhanced in vitro synthesis of polypeptides containing disulfide bonds. In order to improve the performance of in vitro protein synthesis reactions, pre-treatment and redox buffering of the reaction mix is performed in order to optimize the redox potential. Exogenous enzymes that enhance protein folding and disulfide bond formation may also be added to the reaction.
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