Patent 7060720 was granted and assigned to Bristol-Myers Squibb on June, 2006 by the United States Patent and Trademark Office.
The present invention discloses the identification of the novel inhibitors of IMPDH (inosine-5′-monophosphate dehydrogenase). The compounds and pharmaceutical compositions disclosed herein are useful in treating or preventing IMPDH associated disorders, such as transplant rejection and autoimmune diseases.