Patent 7067617 was granted and assigned to the scripps research institute on June, 2006 by the United States Patent and Trademark Office.
Polypeptides that contain from 2 to 12 zinc finger-nucleotide binding regions that bind to nucleotide sequences of the formula (ANN)2–12 are provided. Polynucleotides that encode such polypeptides and methods of regulating gene expression with such polypeptides and polynucleotides are also provided.