Is a
Patent attributes
Current Assignee
Patent Jurisdiction
Patent Number
Patent Inventor Names
Kenneth A. Thomas, Jr.0
Richard L. Kendall0
Date of Patent
July 4, 2006
0Patent Application Number
101010180
Date Filed
March 19, 2002
0Patent Citations Received
Patent Primary Examiner
Patent abstract
The vascular endothelial cell growth factor (VEGF) inhibitors of the present invention are naturally occurring or recombinantly engineered soluble forms with or without a C-terminal transmembrane region of the receptor for VEGF, a very selective growth factor for endothelial cells. The soluble forms of the receptors will bind the growth factor with high affinity but do not result in signal transduction. These soluble forms of the receptor bind VEGF and inhibit its function.
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