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US Patent 7084118 Combination treatment with t-PA variant and low molecular weight heparin

Patent 7084118 was granted and assigned to Genentech on August, 2006 by the United States Patent and Trademark Office.

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Patent abstract

The invention concerns an improved therapeutic regimen for the treatment of thrombolytic disorders, such as acute myocardial infarction (AMI). In particular, the present invention concerns the treatment of thrombolytic disorders, e.g. AMI, with a combination of a tissue plasminogen activator (t-PA) variant having improved fibrin specificity and extended plasma half-life when compared with wild-type human t-PA and a low molecular weight heparin.

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