Patent 7090998 was granted and assigned to AJINOMOTO CO., INC. on August, 2006 by the United States Patent and Trademark Office.
In a method for producing a target substance utilizing a microorganism, which comprises culturing a γ-proteobacterium in a medium to produce and accumulate the target substance in the medium or cells and collecting the target substance, there is used a strain in which the ArcA protein does not normally function in the cell by means of, for example, disruption of the arcA gene on the chromosome.