Is a
Patent attributes
Patent Jurisdiction
Patent Number
Patent Inventor Names
Dennis R. Burton0
Jiri G. Safar0
R. Anthony Williamson0
Stanley B. Prusiner0
Date of Patent
August 22, 2006
0Patent Application Number
103557800
Date Filed
January 30, 2003
0Patent Primary Examiner
Patent abstract
The present invention provides antibodies that specifically bind with a high degree of binding affinity to a native ungulate PrPC and/or a denatured ungulate PrPSc, but not to a native ungulate PrPSc. Preferred antibodies find native bovine PrPC and treated PrPSc but not native bovine PrPSc and can be used in an assay to determine if a sample is infected with infectious prions, i.e. PrPSc.
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