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US Patent 7094765 Antisense restenosis composition and method

Patent 7094765 was granted and assigned to Avi Biopharma, Inc. on August, 2006 by the United States Patent and Trademark Office.

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Patent abstract

The present invention provides an improved method for reducing the risk or severity of restenosis following cardiac angioplasty. The method includes administering to a target vessel region, a morpholino antisense compound having uncharged phosphorus-containing backbone linkages, and spanning the start codon of a human c-myc mRNA. Also disclosed are novel antisense compounds and compositions, and a method for assaying the effectiveness of antisense delivery and uptake to a target vessel region.

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