Is a
Patent attributes
Patent Jurisdiction
Patent Number
Patent Inventor Names
Qiong Cheng0
Luan Tao0
Date of Patent
August 29, 2006
0Patent Application Number
108602910
Date Filed
June 3, 2004
0Patent Primary Examiner
Patent abstract
The present invention provides methods to engineer microorganisms for the production of C30-aldehyde carotenoids. Specifically, various combinations of crtM, sqs, crtN and crtN2 genes from Staphylococcus aureus and Methylomonas sp. 16a can be co-expressed in transformant hosts, leading to the production of diaponeurosporene monoaldehyde, diapocarotene monoaldehyde, and/or diapocarotene dialdehyde. In a preferred embodiment, the genetically engineered pathway is introduced into a strain of Escherichia coli that has been engineered for the expression of carotenoids, and the C30-carotenoid product is diapocarotene dialdehyde.
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