Is a
Patent attributes
Patent Jurisdiction
Patent Number
Patent Inventor Names
David A. Schwartz0
Richard I. Hogrefe0
Date of Patent
September 5, 2006
Patent Application Number
09630060
Date Filed
August 1, 2000
Patent Citations Received
Patent Primary Examiner
Patent abstract
Hydrazino, oxyamino and carbonyl-based reagents and methods for incorporation into oligonucleotides during their solid phase synthesis are provided. Modified oligonucleotides are provided that incorporate the reagents provided here in. Immobilized oligonucleotides and oligonucleotide conjugates that contain covalent hydrazone or oxime linkages are provided. Methods for preparation of surface bound oligonucleotides are provided. Methods for the preparation of oligonucleotide conjugates are also provided.
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