A PLL clock signal generation circuit comprising a phase comparator, a charge pump circuit, a filter circuit, a voltage control oscillator and a divider, wherein a multiple rate control circuit is further included which detects a state of the reference voltage (output from a filter circuit) and controls a change of a multiple rate of a divider according to a state of the detected reference voltage. The multiple rate control circuit further outputs control signal LPFOUT for changing a multiple rate so that the PLL clock signal generation circuit does not deviate from a region capable of locking when being detected of deviation from the region capable of locking by detecting the state of reference voltage.