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US Patent 7112321 Adeno-associated virus-mediated delivery of GDNF to skeletal muscles

Patent 7112321 was granted and assigned to Genzyme on September, 2006 by the United States Patent and Trademark Office.

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Patent abstract

Compositions and methods for delivering GDNF to skeletal muscles to result in a therapeutic effect are disclosed. The compositions and methods use adeno-associated virus (AAV)-based gene delivery systems. The methods are useful for treating motoneuron diseases, such as amyotrophic lateral sclerosis (ALS).

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