Is a
Patent attributes
Patent Jurisdiction
Patent Number
Patent Inventor Names
Donald M. McDonald0
O. Gavin Thurston0
John W. McLean0
Date of Patent
September 26, 2006
0Patent Application Number
101611940
Date Filed
May 28, 2002
0Patent Primary Examiner
Patent abstract
Angiogenic endothelial cells are selectively targeted with lipid/DNA complexes or cationic liposomes containing a substance which affects the targeted cells by inhibiting or promoting their growth. A site of angiogenesis can be precisely located by administering cationic liposomes containing a detectable label. The complexes may comprise nucleotide constructs which are comprised of promoters which are selectively and exclusively activated in the environment of an angiogenic endothelial cell.
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