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US Patent 7115795 Transgenic animals expressing salivary proteins

Patent 7115795 was granted and assigned to University of Guelph on October, 2006 by the United States Patent and Trademark Office.

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Current Assignee
University of Guelph
University of Guelph
Patent Jurisdiction
United States Patent and Trademark Office
United States Patent and Trademark Office
Patent Number
7115795
Date of Patent
October 3, 2006
Patent Application Number
09926375
Date Filed
April 20, 2000
Patent Primary Examiner
‌
Scott D. Priebe
Patent abstract

The invention provides a transgenic animal having within its genome a transgene construct for gastrointestinal tract specific expression of a protein. In a preferred embodiment, the protein is a phytase or a homologue thereof. Such proteins may be heterologous and may be specifically expressed in the salivary gland of the animal by operably linking the nucleic acid sequence encoding the protein with regulatory sequence including a salivary gland protein promoter/enhancer. Also provided are methods of expressing and producing proteins using such nucleic acid constructs. Further, antibodies specific to such proteins and immunological diagnostic kits are also provided.

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