Patent 7119092 was granted and assigned to Smithkline Beecham Limited on October, 2006 by the United States Patent and Trademark Office.
whereinR represents a halogen atom or a C1-4 alkyl group;R1 represents a C1-4 alkyl group;R2 represents hydrogen or a C1-4 alkyl group;R3 represents hydrogen, or a C1-4 alkyl group;R4 represents a trifluoromethyl group;R5 represents hydrogen, a C1-4 alkyl group or C(O)R6;R6 represents C1-4 alkyl, C3-7 cycloalkyl, NH(C1-4 alkyl) or N(C1-4alkyl)2;m is zero or an integer from 1 to 3;n is an integer from 1 to 3 and pharmaceutically acceptable salts and solvates thereof; to processes for their preparation and their use in the treatment of conditions mediated by tachykinins.