Is a
Patent attributes
Current Assignee
Patent Jurisdiction
Patent Number
Patent Inventor Names
Dmitri A. Pissarnitski0
Theodros Asberom0
John W. Clader0
Hubert B. Josien0
Date of Patent
October 17, 2006
0Patent Application Number
102108030
Date Filed
August 1, 2002
0Patent Primary Examiner
Patent abstract
Novel aryl and heteroaryl sulfonamides are disclosed. The sulfonamides, which are gamma secretase inhibitors, are represented by the formula:wherein Ar1 and Ar2 independently represent aryl or heteroaryl and Y represents a bond or a —(C(R3)2)1-3 group. Also disclosed is a method of inhibiting gamma secretase, and a method of treating Alzheimer's disease using the compounds of formula I.
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