Is a
Patent attributes
Current Assignee
Patent Jurisdiction
Patent Number
Patent Inventor Names
Gregory C. Kujoth0
Tomas A. Prolla0
Date of Patent
October 24, 2006
Patent Application Number
11119099
Date Filed
April 29, 2005
Patent Primary Examiner
Patent abstract
A mouse model for mammalian aging is disclosed. In one embodiment, the invention comprises a mouse having a genomic mutation in the exonuclease domain II (ExoII) of a mitochondrial DNA polymerase gamma (PolG) gene, wherein the mutation leads to high levels of mutations in polymerase mtDNA.
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