Is a
Patent attributes
Patent Jurisdiction
Patent Number
Date of Patent
November 21, 2006
Patent Application Number
10360828
Date Filed
February 7, 2003
Patent Citations Received
Patent Primary Examiner
Patent abstract
Compositions are provided that comprise antibody against membrane proteins such as chemokine receptors. In particular, monoclonal human antibodies against human CXCR4 are provided that are capable of inhibiting HIV infection and chemotaxis in human breast cancer cells. The antibodies can be used as prophylactics or therapeutics to prevent and treat HIV infection and cancer, for screening drugs, and for diagnosing diseases or conditions associated with interactions with chemokine receptors.
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