Is a
Patent attributes
Patent Jurisdiction
Patent Number
Patent Inventor Names
Zhu Chen0
Kevin Berman0
Melaine Cobb0
Michelle Hutchinson0
Date of Patent
December 26, 2006
0Patent Application Number
104457350
Date Filed
May 27, 2003
0Patent Primary Examiner
Patent abstract
Compositions and methods are provided for potentiating the activity of the mitogen-activated protein kinase p38. In particular the mitogen-activated protein kinase kinase MEK6, and variants thereof that stimulate phosphorylation of p38 are provided. Such compounds may be used, for example, for therapy of diseases associated with the p38 cascade and to identify antibodies and other agents that inhibit or activate signal transduction via p38.
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