Is a
Patent attributes
Patent Jurisdiction
Patent Number
Patent Inventor Names
Karl H. Willert0
Roeland Nusse0
Date of Patent
December 26, 2006
0Patent Application Number
108167200
Date Filed
April 1, 2004
0Patent Primary Examiner
Patent abstract
Compositions of purified biologically active Wnt proteins are provided. Wnt proteins are found to be hydrophobic and post-translationally modified by addition of a lipid moiety at a conserved cysteine residue. Methods for isolation of Wnt utilize detergents that maintain the solubility of the modified protein.
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