Patent 7169576 was granted and assigned to Bristol-Myers Squibb on January, 2007 by the United States Patent and Trademark Office.
The present application relates to a sensitive and quantitative method using dansylated glutathione as a trapping agent for the detection of reactive metabolites in the field of drug discovery. The fluorescent tag attached to the dansylated glutathione does not impede the ability of glutathione to react with reactive metabolites.