Is a
Patent attributes
Current Assignee
Patent Jurisdiction
Patent Number
Patent Inventor Names
Hans Gaus0
Achim Krotz0
Brett Turney0
Daniel Capaldi0
Date of Patent
January 30, 2007
Patent Application Number
10403692
Date Filed
March 31, 2003
Patent Primary Examiner
Patent abstract
A process of manufacturing oligonucleotides includes a 5′-deblocking step in which the 5-blocking group is removed with dichloroacetic acid that is essentially free of chloral. The process is useful for making oligonucleotides that are substantially free of chloral adducts.
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