A clip applying device for the insertion and pinching of a medical clip within a mammalian body portion. The device comprises a housing supporting a proximal end of a delivery tube of the device. A pair of pinchable jaws are movably arranged at a distal end of the delivery tube. The device contains a plurality of preformed clips of a first width, the clips having leg portions, the clips also being movably disposed within the delivery tube between the housing and the jaws. A tool adjacent the jaws is arranged to enlarge the clips from a first width to a wider second width, as the clips emerge from the delivery tube.