Is a
Patent attributes
Patent Jurisdiction
Patent Number
Patent Inventor Names
Shinsaku Nakagawa0
Hakuo Ikegami0
Tadanori Mayumi0
Yasuo Tsutsumi0
Date of Patent
February 20, 2007
0Patent Application Number
106681780
Date Filed
September 24, 2003
0Patent Citations Received
Patent Primary Examiner
Patent abstract
Disclosed is a physiologically active complex which comprises a proteinaceous part with TNF activity and a high molecular part bound artificially to the N-terminus of the proteinaceous part. The proteinaceous part in the complex has the amino acid sequence of SEQ ID NO:2 where Xaa is a member selected from the group consisting of asparagine, alanine, arginine, serine, threonine, proline, methionine, and leucine; while the high molecular part in the complex is a homopolymer of polyethylene glycol, copolymer of polyethylene glycol, or a derivative thereof.
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