Is a
Patent attributes
Patent Jurisdiction
Patent Number
Date of Patent
April 10, 2007
Patent Application Number
11145451
Date Filed
June 3, 2005
Patent Primary Examiner
Patent abstract
DNA constructs and other compositions and methods for controlling gene expression in eukaryotic cells and organisms are derived from bacterial quorum sensing systems. One or more cis elements from the luxI promoter (“lux box”) or a functionally similar sequence are incorporated in a eukaryotic promoter. A receptor protein from the LuxR family of transcriptional regulators, upon binding an acylated homoserine lactone (AHL) compound, interacts with the lux box, modulating the activity of the promoter.
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