Patent 7205402 was granted and assigned to Bristol-Myers Squibb on April, 2007 by the United States Patent and Trademark Office.
The present invention provides novel methods for the synthesis of (S)-6-chloro-4-cyclopropylethynyl-4-trifluoromethyl-1,4-dihydro-2H-3,1-benzoxazin-2-one of formula (III)