US Patent 7205405 Process for preparing 3-(2-(4-(6-fluorobenzo(d)isoxazol-3-yl)-piperidin-1-yl)-ethyl)-2-methyl- 6,7,8,9-tetrahydro-4h-pyrido-(1,2-a)pyrimidin-4-one

Patent 7205405 was granted and assigned to Ferrer on April, 2007 by the United States Patent and Trademark Office.

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Patent

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Current Assignee

Ferrer

Patent Jurisdiction

United States Patent and Trademark Office

Patent Number

7205405

Date of Patent

April 17, 2007

Patent Application Number

10503478

Date Filed

March 3, 2003

Patent Primary Examiner

‌

Deepak Rao

Patent abstract

The process consists in condensing (2-methyl-6,7,8,9-tetrahydro-4 H-pyrido-[1,2-a]pyrimidin-3-yl)-acetaldehyd with 6-fluoro-3-piperidinyl)-1,2-benzisoxazole to yield the intermediate enamine, 3-{2-[4-(6-fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]vinyl}-2-methyl-6,7,8,9-tetrahydro-pyrido[1,2,-a]pyrimidin-4 -one followed by reduction of such an enamine.

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