Is a
Patent attributes
Patent Jurisdiction
Patent Number
Date of Patent
April 24, 2007
0Patent Application Number
103943870
Date Filed
March 20, 2003
0Patent Citations Received
Patent Primary Examiner
Patent abstract
Immunostimulatory polynucleotide-immunomodulatory molecule conjugate compositions are disclosed. These compositions include a polynucleotide that is linked to an immunomodulatory molecule, which molecule comprises an antigen and may further comprise immunomodulators such as cytokines and adjuvants. The polynucleotide portion of the conjugate includes at least one immunostimulatory oligonucleotide nucleotide sequence (ISS). Methods of modulating an immune response upon administration of the polynucleotide-immunomodulatory conjugate preparation to a vertebrate host are also disclosed.
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