US Patent 7208479 Peritoneal dialysis solution containing modified icodextrins

Patent 7208479 was granted and assigned to Baxter International Inc. on April, 2007 by the United States Patent and Trademark Office.

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Patent

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Current Assignee

Patent Jurisdiction

United States Patent and Trademark Office

Patent Number

72084790

Patent Inventor Names

Annamaria Naggi0

Giangiacomo Torri0

Enrico Petrella0

Benito Casu0

Date of Patent

April 24, 2007

Patent Application Number

108245490

Date Filed

April 14, 2004

Patent Primary Examiner

‌

Patrick Lewis

Patent abstract

The present invention provides a peritoneal dialysis solution that contains heat stable osmotic agents such as D-glucitols, gluconic acids and alkylglycosides produced the reduction, oxidation or glycosylation of icodextrins respectively. As a result, osmotic agents that are stable under autoclaving or heat sterilization conditions are provided which reduces the amount of bioincompatible materials in the sterilized peritoneal dialysis solutions. Methods of preparing the D-glucitols, gluconic acids and alkylglycosides are disclosed.

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