Is a
Patent attributes
Patent Jurisdiction
Patent Number
Patent Inventor Names
Tetsuji Sudoh0
Kenji Kangawa0
Mika Takashima0
Naoto Minamino0
Atsushi Izumi0
Hisayuki Matsuo0
Keiji Maekawa0
Date of Patent
May 1, 2007
0Patent Application Number
081928000
Date Filed
February 7, 1994
0Patent Primary Examiner
Patent abstract
A physiologically active polypeptide derived from human brain and a DNA fragment comprising the base sequence encoding the polypeptide are disclosed. The polypeptide possesses excellent smooth muscle relaxation activity, diuretic or natriuretic activity, and vasodepressor activity, and is thus useful as a medicine for curing circulation diseases, e.g. cardiac edema, nephric edema, hepatic edema, pulmonary edema, hypertension, congestive heat failure, and acute and chronic renal failure.
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