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US Patent 7214493 Polynucleotides encoding humanized antibodies against human 4-1BB

Patent 7214493 was granted and assigned to Bristol-Myers Squibb on May, 2007 by the United States Patent and Trademark Office.

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Patent abstract

A humanized antibody that binds to human 4-1BB and that allows binding of human 4-1BB to a human 4-1BB ligand. In one aspect, the antibody is an IgG4 antibody. Also provided is a method for treating cancer in a subject comprising administering a therapeutically effective amount of the antibody to said subject.

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