Is a
Patent attributes
Patent Jurisdiction
Patent Number
Date of Patent
May 15, 2007
Patent Application Number
10990138
Date Filed
November 16, 2004
Patent Primary Examiner
Patent abstract
Provided are methods of producing phosphitylated compounds, including 3′-O-phosphoramidites, comprising the step of reacting a hydroxyl-containing compound with a phosphitylating agent in the presence of a phosphitylation activator selected from the group consisting of: (1) acid-base complexes derived from an amine base of Formula II
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