Is a
Patent attributes
Patent Jurisdiction
Patent Number
Patent Inventor Names
Zdenka L. Jonak0
James A. Fornwald0
Jonathan A. Terrett0
Stephen H. Trulli0
Gregg A. Hastings0
Date of Patent
May 22, 2007
0Patent Application Number
093736580
Date Filed
August 13, 1999
0Patent Primary Examiner
Patent abstract
The present invention relates to novel anti-angiogenic proteins, related to thrombospondin. More specifically, isolated nucleic acid molecules are provided encoding human METH1 and METH2. METH1 and METH2 polypeptides are also provided, as are vectors, host cells and recombinant methods for producing the same. Also provided are diagnostic methods for the prognosis of cancer and therapeutic methods for treating individuals in need of an increased amount of METH1 or METH2. Also provided are methods for inhibiting angiogenesis using METH1 or METH2.
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