Is a
Patent attributes
Current Assignee
Patent Jurisdiction
Patent Number
Patent Inventor Names
Markus Albers0
Jörg Baumgarten0
Ulf Brüggemeier0
Thomas-J. Schulze0
Andreas Schoop0
Hans-Georg Lerchen0
Date of Patent
May 22, 2007
0Patent Application Number
100702080
Date Filed
August 28, 2000
0Patent Primary Examiner
Patent abstract
The present invention relates to cytostatics which have a tumour-specific action as a result of linkage to αvβ3 integrin antagonists via preferred linking units. The preferred linking units guarantee serum stability of the conjugate of cytostatic and αvβ3 integrin antagonist and at the same time the desired intracellular action in tumour cells as a result of their enzymatic or hydrolytic cleavability with release of the cytostatic.
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