Is a
Patent attributes
Current Assignee
0
Patent Jurisdiction
Patent Number
Patent Inventor Names
Frances Kay Huebner0
Carlo M. Croce0
Date of Patent
May 22, 2007
0Patent Application Number
109132280
Date Filed
August 6, 2004
0Patent Citations Received
Patent Primary Examiner
Patent abstract
The present invention relates to nucleotide sequences of FHIT genes and amino acid sequences of their encoded proteins, as well as derivatives and analogs thereof, and antibodies thereto. The FHIT gene sequence is mutated in diseases involving cell overproliferation, particularly malignancies of the digestive tract. The present invention further relates to the use of FHIT genes and their encoded proteins as diagnostic and therapeutic reagents for the detection and treatment of disease states associated with cell overproliferation.
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