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US Patent 7223741 Immunostimulatory nucleic acid molecules

Patent 7223741 was granted and assigned to University of Iowa on May, 2007 by the United States Patent and Trademark Office.

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Patent abstract

Nucleic acid sequences containing unmethylated CpG dinucleotides that modulate an immune response including stimulating a Th1 pattern of immune activation, cytokine production, NK lytic activity, and B cell proliferation are disclosed. The sequences are also useful a synthetic adjuvant.

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