Is a
Patent attributes
Current Assignee
Patent Jurisdiction
Patent Number
Patent Inventor Names
Leu-Fen H. Lin0
Jack Lile0
Franklin D. Collins0
Daniel H. Doherty0
Susan Bektesh0
Date of Patent
June 5, 2007
0Patent Application Number
081821830
Date Filed
September 17, 1992
0Patent Citations Received
Patent Primary Examiner
Patent abstract
A novel neurotrophic factor referred to as glial cell line-derived neurotrophic factor (GDNF) has been identified and isolated from serum free growth conditioned medium of B49 glioblastoma cells. Rat and human genes encoding GDNF have been cloned and sequenced. A gene encoding GDNF has been subcloned into a vector, and the vector has been used to transform a host cell in order to produce biologically active GDNF in a recombinant DNA process.
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