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US Patent 7229606 Diagnostic imaging contrast agents with extended blood retention

Patent 7229606 was granted and assigned to EPIX Pharmaceuticals, Inc. on June, 2007 by the United States Patent and Trademark Office.

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Patent abstract

The present invention relates to contrast agents for diagnostic imaging with prolonged blood retention. In particular, this invention relates to novel compounds that are characterized by an image enhancing moiety (IEM); a protein plasma binding moiety (PPBM); and a blood half-life extending moiety (BHEM). This invention also relates to pharmaceutical compositions comprising these compounds and to methods of using the compounds and compositions for blood half-life extension and contrast enhancement of diagnostic imaging.

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