Is a
Patent attributes
Patent Jurisdiction
Patent Number
Patent Inventor Names
Veronique A. Dartois0
Manoj Kumar0
Fernando Valle0
James A. Hoch0
Date of Patent
June 12, 2007
0Patent Application Number
107872670
Date Filed
February 25, 2004
0Patent Primary Examiner
Patent abstract
The invention provides isolated nucleic acid molecules encoding polypeptides having 2,5-DKG permease activity, and oligonucleotides therefrom. The isolated nucleic acid molecules can be expressed in appropriate bacterial cells to enhance the production of 2-KLG, which can subsequently be converted to ascorbic acid. Further provided are isolated polypeptides having 2,5-DKG permease activity, immunogenic peptides therefrom, and antibodies specific therefor. The invention also provides methods of identifying novel 2,5-DKG permeases.
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