Patent 7230083 was granted and assigned to Smithkline Beecham Limited on June, 2007 by the United States Patent and Trademark Office.
This invention relates to novel humanized and other recombinant or engineered antibodies or monoclonal antibodies to the vitronectin αvβ3 receptor and to the genes encoding same. Such antibodies are useful for the therapeutic and/or prophylactic treatment of αvβ3-mediated disorders, such as restenosis, in human patients.