US Patent 7232810 2-methylene-19-nor-vitamin D2 compounds
Patent 7232810 was granted and assigned to Wisconsin Alumni Research Foundation on June, 2007 by the United States Patent and Trademark Office.
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2-Methylene-19-nor-24(S) and 24(R) derivatives of 1α,25-dihydroxyvitamin D2 are disclosed. These compounds are characterized by minimal bone calcium mobilization activity and relatively high intestinal calcium transport activity. This results in novel therapeutic agents for the treatment of diseases such as renal osteodystrophy, autoimmune diseases, and osteoporosis. These compounds also exhibit pronounced activity in arresting the proliferation of undifferentiated cells and inducing their differentiation to the monocyte thus evidencing use as anticancer agents and for use treating skin diseases such as psoriasis
US Patent 07232810 2-methylene-19-nor-vitamin D2 compounds US Patent 7232810 2-methylene-19-nor-vitamin D2 compounds
US Patent 07232810 2-methylene-19-nor-vitamin D2 compounds
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