Is a
Patent attributes
Current Assignee
Patent Jurisdiction
Patent Number
Patent Inventor Names
Masaomi Umeda0
Mitsuiyuki Shimada0
Sachiko Sakakibara0
Takashi Yoshiro0
Takuya Shintani0
Timothy B. Lowinger0
Toshiki Murata0
Tsutomu Masuda0
...
Date of Patent
June 19, 2007
0Patent Application Number
112407280
Date Filed
September 30, 2005
0Patent Primary Examiner
Patent abstract
This invention is to provide a process for producing 2-amino-4,6-disubstituted nicotinic acid ester analogs and salts thereof, comprising the reaction shown by the following scheme. The ester analogs can be prepared in one pot, and in good yield by using tertiary alkyl cyanoacetate. Furthermore, the method is useful for preparing derivatives of various analogs of the ester, e.g. alkyl substituted and aryl substituted analogs.
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