US Patent 7235353 Predicting hepatotoxicity using cell based assays

Patent 7235353 was granted and assigned to Cytokinetics on June, 2007 by the United States Patent and Trademark Office.

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Patent

Patent attributes

Current Assignee

Cytokinetics

Patent Jurisdiction

United States Patent and Trademark Office

Patent Number

72353530

Patent Inventor Names

Jinhong Fan0

Larry C. Mattheakis0

Aibing Rao0

Eugeni Vaisberg0

Cynthia Lynn Adams0

Gregg Peter Solar0

Jay Kenneth Trautman0

Date of Patent

June 26, 2007

Patent Application Number

106234860

Date Filed

July 18, 2003

Patent Primary Examiner

‌

Herbert J. Lilling

Patent abstract

Cell based assays are used to assess the hepatotoxicity of a stimulus. Imaging technologies are used to analyze the effects of a stimulus on hepatocytes. Image analysis may characterize the stimulus on the basis of whether it is hepatotoxic, and if so what type of pathology is exhibited; e.g., apoptosis, necrosis, cholestasis, and/or steatosis.

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