Is a
Patent attributes
Patent Jurisdiction
Patent Number
Date of Patent
June 26, 2007
Patent Application Number
10132163
Date Filed
April 26, 2002
Patent Primary Examiner
Patent abstract
The present invention is related to anthranilamides of formula I,in which R(1) to R(7) have the meanings indicated herein, a process for their preparation, their use as medicaments, and pharmaceutical preparations containing them. The compounds act on the Kv1.5 potassium channel and inhibit a potassium current which is referred to as the ultra-rapidly activating delayed rectifier in the atrium of the human heart. The compounds are therefore suitable for use as novel antiarrhythmic agents for the treatment and prophylaxis of atrial arrhythmias (e.g., atrial fibrillation (AF) or atrial flutter).
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