Is a
Patent attributes
Patent Jurisdiction
Patent Number
Patent Inventor Names
Judith Aronhime0
Arina Ceausu0
Anita Lieberman0
Date of Patent
June 26, 2007
0Patent Application Number
109472270
Date Filed
September 23, 2004
0Patent Primary Examiner
Patent abstract
The present invention provides an improved process for preparing modafinil, whereby it may be isolated in high purity by a single crystallization. The process produces modafinil free of sulphone products of over-oxidation and other byproducts. The invention further provides new crystalline Forms II–VI of modafinil and processes for preparing them. Each of the new forms is differentiated by a unique powder X-ray diffraction pattern. The invention further provides pharmaceutical compositions containing novel modafinil Forms II–IV and VI.
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